| | | Monday, August 24th, 1953 | | Placed SP Juan Gutiérrez on the 15-day disabled list. |
| Tuesday, July 7th, 1953 | | Placed SS Vincente Ortíz on the 15-day disabled list. |
| Monday, June 15th, 1953 | | Promoted LF Carson Poole to Double A San Antonio. | | Received SP Luis Chávez from Double A San Antonio. | | Received RF Ray Dickson from Double A San Antonio. | | Drafted 2B Nick Smith in the 1953 first-year player draft (Round 6, Pick 11, 91st overall pick). | | Drafted SP John Moser in the 1953 first-year player draft (Round 7, Pick 11, 107th overall pick). | | Drafted CL David Steele in the 1953 first-year player draft (Round 9, Pick 11, 139th overall pick). | | Drafted MR Bob Hart in the 1953 first-year player draft (Round 10, Pick 11, 155th overall pick). |
| Friday, June 12th, 1953 | | Placed 3B Felipe Aguilar on the 15-day disabled list. |
| Thursday, May 7th, 1953 | | Placed SP Ben McGinnis on the 15-day disabled list. |
| Monday, March 23rd, 1953 | | Activated 2B John Walker from the disabled list. |
| Sunday, January 4th, 1953 | | Activated 3B Sergio Matos from the disabled list. |
| Saturday, December 20th, 1952 | | Placed 3B Sergio Matos on the 15-day disabled list. |
| Friday, October 31st, 1952 | | Released MR Bob Harris. |
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