| | | Monday, August 24th, 1959 | | Placed 3B Eduardo González on the 15-day disabled list. |
| Thursday, July 16th, 1959 | | Activated SP José Luna from the disabled list. |
| Monday, June 15th, 1959 | | Promoted SP José Cabrera to Double A San Antonio. | | Received MR José Martínez from Double A San Antonio. | | Received SS Michael Bauer from Double A San Antonio. | | Promoted 2B Nick Smith to Double A San Antonio. | | Received RF Marco Weerheim from Double A San Antonio. | | Drafted SS Jimmy Green in the 1959 first-year player draft (Round 6, Pick 5, 92nd overall pick). | | Drafted SP Ned Sherer in the 1959 first-year player draft (Round 7, Pick 5, 108th overall pick). | | Drafted SS Terence Ward in the 1959 first-year player draft (Round 8, Pick 5, 124th overall pick). | | Drafted MR Bobby Walter in the 1959 first-year player draft (Round 9, Pick 5, 140th overall pick). | | Drafted 2B Lance Cochrane in the 1959 first-year player draft (Round 10, Pick 5, 156th overall pick). | | Promoted RF Marco Weerheim to Double A San Antonio. | | Received 1B Miguel Ferrer from Double A San Antonio. |
| Saturday, May 2nd, 1959 | | Placed SP Pete Collins on the 15-day disabled list. |
| Monday, April 20th, 1959 | | Placed SP José Luna on the 15-day disabled list. |
| Saturday, January 24th, 1959 | | Activated SS Dani Martínez from the disabled list. |
| Friday, January 9th, 1959 | | Placed SS Dani Martínez on the 15-day disabled list. |
| Monday, October 6th, 1958 | | Activated LF Dani Sánchez from the disabled list. |
|
|
