| Thursday, April 9th, 1981 |
| Demoted MR Edward Taylor to Triple A Keswick. |
| Demoted MR Min Mar to Triple A Keswick. |
| Demoted MR Franco Pérez to Triple A Keswick. |
| Promoted CL David Christensen from Double A Alice to Triple A Keswick. |
| Demoted C Eduardo López to Triple A Keswick. |
| Promoted C Daryl Wilkinson from Double A Alice to Triple A Keswick. |
| Demoted 2B David Brown to Triple A Keswick. |
| Demoted 3B Franklin Pelley to Triple A Keswick. |
| Demoted 1B Mo Tsou to Triple A Keswick. |
| Demoted 1B Vincente Díaz to Triple A Keswick. |
| Demoted RF Don Miles to Triple A Keswick. |
| Demoted CF Andre Nattrass to Triple A Keswick. |
| Demoted RF Jason Barnett to Triple A Keswick. |
| Promoted CF Mike Sweeney from Double A Alice to Triple A Keswick. |
| Promoted RF Rick Stephens from Double A Alice to Triple A Keswick. |
| Promoted 3B Martín Pacheco from Double A Alice to Triple A Keswick. |
| Promoted LF Roger Clark from Double A Alice to Triple A Keswick. |
| Promoted SP Vasco Galindo from Single A Costa Mesa to Double A Alice. |
| Promoted SP António Navarro from Single A Costa Mesa to Double A Alice. |
| Promoted MR Charlie Good from Single A Costa Mesa to Double A Alice. |
| Promoted C Patrick Simmons from Single A Costa Mesa to Double A Alice. |
| Promoted 3B Carlos Márquez from Single A Costa Mesa to Double A Alice. |
| Promoted CF Bob Smith from Single A Costa Mesa to Double A Alice. |
| Promoted 3B Mike Bradley from Single A Costa Mesa to Double A Alice. |
| Promoted 1B Bob Jones from Single A Costa Mesa to Double A Alice. |
| Promoted 1B Andy Scott from Single A Costa Mesa to Double A Alice. |
| Promoted LF Cristián Rodríguez from Single A Costa Mesa to Double A Alice. |
| Promoted LF Ed Hughes from Single A Costa Mesa to Double A Alice. |
| Promoted MR Félix Moreno from Single A Costa Mesa to Double A Alice. |
| Signed free agent C John O'Toole to a minor league contract. |
| Signed free agent C Javier Martínez to a minor league contract. |
| Signed free agent 3B Ken Hamilton to a minor league contract. |
| Signed free agent 2B Ernesto Delgado to a minor league contract. |
| Signed free agent RF Jesse O'Connor to a minor league contract. |
| Signed free agent CF Vernon Pye to a minor league contract. |
| Signed free agent LF Jim Bennett to a minor league contract. |
| Signed free agent 1B Rafael Adame to a minor league contract. |
| Signed free agent 2B Jeff James to a minor league contract. |
| Signed free agent RF Sterling MacLean to a minor league contract. |
| Signed free agent CF Ted Murphy to a minor league contract. |
| Promoted MR Vasco Galindo from Double A Alice to Triple A Keswick. |
| Promoted CF Ted Murphy from Single A Costa Mesa to Triple A Keswick. |
| Demoted SP Min Mar from Triple A Keswick to Double A Alice. |
| Promoted CL Alfredo Flores from Single A Costa Mesa to Double A Alice. |
| Promoted 2B Jeff James from Single A Costa Mesa to Double A Alice. |
| Promoted CF Vernon Pye from Single A Costa Mesa to Double A Alice. |
| Demoted LF Roger Clark from Triple A Keswick to Double A Alice. |
| Promoted LF Jim Bennett from Single A Costa Mesa to Double A Alice. |
| Promoted 1B Rafael Adame from Single A Costa Mesa to Double A Alice. |
| Demoted MR Dave Palmer from Double A Alice to Single A Costa Mesa. |
| Demoted 3B Carlos Márquez from Double A Alice to Single A Costa Mesa. |
| Demoted 3B Mike Bradley from Double A Alice to Single A Costa Mesa. |
| Demoted 1B Domingo Marín from Double A Alice to Single A Costa Mesa. |
| Demoted RF Ed Hughes from Double A Alice to Single A Costa Mesa. |
| Demoted SP Charles Lang from Double A Alice to Single A Costa Mesa. |
