| Monday, February 2nd, 1981 | | SP Mark Isobel was injured when he fell down the stairs while sleepwalking. The Diagnosis: oblique strain. He's expected to miss about 3-4 weeks. |
| Thursday, September 11th, 1980 | | LF Zach Wakeham was injured while running the bases. The Diagnosis: torn meniscus (knee). He's expected to miss about 6 weeks. |
| Tuesday, September 9th, 1980 | | MR Barthelemy Saro was injured while pitching. The Diagnosis: forearm soreness. This is a day-to-day injury expected to last 5 days. |
| Wednesday, September 3rd, 1980 | | SP Ted Lamoreaux was injured while running the bases. The Diagnosis: hip flexor strain. He's expected to miss about 2-3 weeks. |
| Wednesday, August 27th, 1980 | | 3B Pedro Balderas was injured in a collision at a base. The Diagnosis: oblique strain. He's expected to miss about 3 weeks. |
| Thursday, August 21st, 1980 | | SP Carlos Palmeiro was injured while pitching. The Diagnosis: forearm soreness. This is a day-to-day injury expected to last 3 days. |
| Sunday, August 17th, 1980 | | SP Mark Isobel was injured while pitching. The Diagnosis: strained shoulder. He's expected to miss about 8 weeks. |
| Thursday, August 14th, 1980 | | SS Orlando Méndez was injured while running the bases. The Diagnosis: strained quadriceps. This is a day-to-day injury expected to last 4 days. |
| Wednesday, July 30th, 1980 | | SP Félix Cortés was injured while pitching. The Diagnosis: partially torn labrum. He's expected to miss about 3-4 months. |
| Thursday, July 24th, 1980 | | SP Ted Lamoreaux was injured while pitching. The Diagnosis: sore thumb. This is a day-to-day injury expected to last 3 days. | | MR Barthelemy Saro was injured while pitching. The Diagnosis: mild oblique strain. This is a day-to-day injury expected to last one week. |
| Thursday, July 17th, 1980 | | SS Ralph Landry was injured in a collision at a base. The Diagnosis: torn ankle ligaments. He's expected to miss about 5-6 weeks. |
| Wednesday, July 9th, 1980 | | LF Manuel Marrero was injured while running the bases. The Diagnosis: strained back. This is a day-to-day injury expected to last 5 days. |
| Tuesday, July 8th, 1980 | | 2B Frank Thompson was injured while running the bases. The Diagnosis: hamstring soreness. He's expected to miss about 5 days. |
| Sunday, June 29th, 1980 | | 1B Orlando Méndez was injured while running the bases. The Diagnosis: hamstring strain. He's expected to miss about 6-7 weeks. |
| Tuesday, June 10th, 1980 | | SP Ted Lamoreaux was injured while pitching. The Diagnosis: torn meniscus (knee). He's expected to miss about 7-8 weeks. |
| Sunday, June 1st, 1980 | | RF Vincent Ward was injured while running the bases. The Diagnosis: back stiffness. This is a day-to-day injury expected to last 1-2 weeks. |
| Thursday, May 29th, 1980 | | Pedro Balderas has suffered a setback in his recovery. He is not expected to recover for another 1-2 weeks. |
| Tuesday, May 27th, 1980 | | SP Carlos Palmeiro was injured while throwing the ball. The Diagnosis: herniated disc (neck). This is a day-to-day injury expected to last 1-2 weeks. |
| Monday, May 26th, 1980 | | LF Manuel Marrero was injured while running the bases. The Diagnosis: ankle soreness. He's expected to miss about 4 days. |
| Tuesday, May 20th, 1980 | | SS Miguel Santos was injured in a collision at a base. The Diagnosis: knee contusion. He's expected to miss about 1-2 weeks. |
| Saturday, May 17th, 1980 | | 3B Pedro Balderas was injured on a defensive play. The Diagnosis: sprained finger. He's expected to miss about 3 weeks. |
| Thursday, May 15th, 1980 | | SS Orlando Méndez was injured while running the bases. The Diagnosis: strained back. This is a day-to-day injury expected to last 3 days. |
| Sunday, May 4th, 1980 | | MR Xiu-tou Chao was injured while pitching. The Diagnosis: sore elbow. This is a day-to-day injury expected to last 5 days. |
| Tuesday, April 22nd, 1980 | | LF Ray Sims was injured while throwing the ball. The Diagnosis: herniated disc (back). This is a day-to-day injury expected to last one week. |
| Tuesday, April 1st, 1980 | | LF Alfred Williams was injured while running the bases. The Diagnosis: back tightness. This is a day-to-day injury expected to last 4 days. |
| Saturday, March 29th, 1980 | | LF Lucas Avery was injured while throwing the ball. The Diagnosis: biceps strain. He's expected to miss about 5 weeks. |
| Wednesday, March 26th, 1980 | | 1B Andy Thomas was injured while running the bases. The Diagnosis: bruised finger. This is a day-to-day injury expected to last 1 day. |
| Sunday, March 23rd, 1980 | | 1B Andy Thomas was injured while running the bases. The Diagnosis: bruised heel. This is a day-to-day injury expected to last 3 days. |
| Wednesday, March 12th, 1980 | | SP Ted Lamoreaux was injured after being scratched by a cat. The Diagnosis: undisclosed injury. He's expected to miss about 3 months. |
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