| | | Saturday, August 16th, 1980 | | Placed LF Dave Bowers on the 15-day disabled list. |
| Wednesday, August 13th, 1980 | | Activated 3B José Rivera from the disabled list. |
| Friday, July 11th, 1980 | | Placed 3B José Vásquez on the 15-day disabled list. |
| Sunday, June 29th, 1980 | | Activated 2B Randy Webb from the disabled list. |
| Saturday, June 21st, 1980 | | Placed 3B José Rivera on the 15-day disabled list. | | Placed RF Roberto Ramírez on the 15-day disabled list. |
| Sunday, June 15th, 1980 | | Promoted RF José Bruno to Double A Eagle Pass. | | Promoted CF Quentin Hall to Double A Eagle Pass. | | Drafted MR Harold White in the 1980 first-year player draft (Round 6, Pick 7, 111st overall pick). | | Drafted C César Contreras in the 1980 first-year player draft (Round 7, Pick 7, 132nd overall pick). | | Drafted RF Dave Bowers in the 1980 first-year player draft (Round 8, Pick 7, 152nd overall pick). | | Drafted SP Travis Nicholson in the 1980 first-year player draft (Round 9, Pick 7, 172nd overall pick). | | Drafted SP Paul Morton in the 1980 first-year player draft (Round 10, Pick 7, 192nd overall pick). |
| Saturday, June 14th, 1980 | | Placed 2B Randy Webb on the 15-day disabled list. |
| Monday, January 21st, 1980 | | Activated SP Matt Forrest from the disabled list. |
| Tuesday, December 18th, 1979 | | Activated SP Nick Wooten from the disabled list. |
| Wednesday, September 5th, 1979 | | Activated 3B José Rivera from the disabled list. |
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